Table 1.
Unknown (X) Multi Analyte Profiling (xMAP) results for 17 inflammation biomarkers in HEp-2 cells in 2 days post-treatment. Normalization was carried out as a ratio of mean fluorescence intensity (MFI) for wells after incubation with the nanosilver to MFI of control intact HEp-2 cells.
| Th1 | Th2 | Th17 | Others | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Inflammation Biomarkers | IFNγ | TNFα | IL-1β | IL-12(p70) | IL-2 | IL-4 | IL-5 | IL-6 | IL-7 | IL-8 | IL-10 | IL-13 | IL-17A | G-CSF | GM-CSF | MCP-1 (MCAP) | MIP-1β |
| AgNO3 | 1.03 | 1.15 ↑ | 1.38 ↑ | 0.70 | 0.74 | 0.84 | 0.88 | 0.85 | 0.70 | 3.71 ↑ | 0.78 | 0.81 | 0.97 | 1.12 ↑ | 0.92 | 1.19 ↑ | 1.17 ↑ |
| AgNP-BSA | 0.76 | 0.72 | 0.70 | 0.70 | 0.82 | 0.74 | 0.70 | 0.75 | 0.50 | 0.64 | 0.78 | 0.69 | 0.76 | 0.78 | 0.79 | 0.85 | 0.76 |
| AgNP-Fb | 0.72 | 0.65 | 1.00 | 0.72 | 0.78 | 0.75 | 0.82 | 0.75 | 0.55 | 1.00 | 0.77 | 0.83 | 0.84 | 1.00 | 0.83 | 1.15 ↑ | 0.97 |
| AgNP-IgG | 0.68 | 0.51 | 2.11 ↑ | 0.54 | 0.48 | 0.43 | 0.60 | 0.41 | 0.44 | 0.34 | 0.54 | 0.50 | 0.97 | 1.20 ↑ | 0.83 | 0.76 | 0.66 |