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. 2021 Aug 25;10(9):1348. doi: 10.3390/antiox10091348

Figure 4.

Figure 4

(a) Effect of HT, HT-Ac, and HT-Et treatment of PC-3 (20 µM, 10 days) and 22Rv1 (10 µM, 14 days) cells in the clonogenic assay. Data are expressed as number of colonies (percent of control, set at 100%) and represent the mean ± SEM (4 experiments). Asterisks indicate significant differences compared to the control value: ** p < 0.01, *** p < 0.001; (b) Effect of HT, HT-Ac, and HT-Et treatment of PC-3 (20 µM, 14 days) and 22Rv1 (10 µM, 14 days) in the size of prostatospheres. Data represent the mean area ± SEM (4 experiments). Asterisks indicate significant differences to the control value: ** p < 0.01, *** p < 0.001. Abbreviations: HT, Hydroxytyrosol; HT-Ac, hydroxytyrosyl acetate; HT-Et, ethyl hydroxytyrosyl ether.