Scheme 6.
Synthetic route to POMO (13). Reagents and conditions: (a) cinnamyl bromide, NaH, DMF, 0 °C; (b) hydrogenation over Pd/C, glacial acetic acid, r.t., 40 psi; (c) 3-O-ether cleavage, refluxing 48% HBr solution.
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