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. 2021 Aug 30;14(9):882. doi: 10.3390/ph14090882

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Overall survival (OS) estimated according to the expression level of integrin α5 and the completion of the Stupp protocol. Kaplan–Meier survival analysis for high and low expression levels of integrin α5 in the all cohort (a) in patients treated by the Stupp protocol (b) and in patients who completed the Stupp protocol (c); HR: hazard ratio in univariate analysis; HR_adj: adjusted hazard ratio in multivariate analysis; CI: confidence interval. Survivals were compared using the log-rank (Mantel–Cox) test. p-values < 0.05 were considered as significant.