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. 2021 Sep 13;13(9):1461. doi: 10.3390/pharmaceutics13091461

Table 1.

The influence of synthesis parameters on the main characteristics of CS/PVA hydrogels.

Sample Code Time (h) GF, % SReq *, g/g Elastic Modulus **
3c 6c Water PBS 6.8 (kPa) R2
CS0.5/PVA1E1 (24) 52.8 (±1.3) 61.6 (±1.4) 72 (±3) 67 (±4) 2.9 (±0.4) 0.9895
CS0.5/PVA1E2 58 (±2) 66.8 (±1.2) 64 (±2) 62 (±2) 6.1 (±0.3) 0.9906
CS0.5/PVA1B1 38 (±3) 45.8 (±1.3) 82 (±3) 75 (±2) 2.6 (±0.2) 0.9528
CS0.5/PVA1B2 43.3 (±1.2) 52.2 (±1.1) 79 (±3) 73 (±2) 9.8 (±0.4) 0.9874
CS1/PVA1E1 54.1 (±0.9) 68.5 (±1.2) 61 (±3) 48.1 (±1.1) 20.7 (±1.5) 0.9919
CS1/PVA1E2 58.2 (±1.2) 69 (±3) 48 (±3) 45.3 (±0.5) 27.4 (±0.5) 0.9942
CS1/PVA1B1 41.2 (±0.8) 57 (±2) 75 (±2) 65 (±2) 10.8 (±0.1) 0.9383
CS1/PVA1B2 56 (±2) 67 (±3) 69 (±2) 49 (±2) 15.1 (±0.6) 0.9908
CS1/PVA0.5E1 64 (±3) 78 (±5) 49 (±3) 44.9 (±1.4) 17.1 (±1.3) 0.9907
CS1/PVA0.5E2 69 (±4) 81 (±5) 46 (±3) 42.3 (±1.1) 18.7 (±1.5) 0.9954
CS1/PVA0.5B1 62 (±3) 74 (±5) 91 (±5) 74.0 (±1.1) 14.7 (±1.2) 0.9885
CS1/PVA0.5B2 62 (±3) 76 (±5) 69 (±3) 65.9 (±1.1) 14.6 (±1.4) 0.9278
CS0.5/PVA1E1 (48) 55 (±2) 70 (±4) 68 (±3) 65 (±3) 3.2 (±1.2) 0.9295
CS0.5/PVA1E2 60 (±2) 73 (±4) 61 (±3) 49 (±2) 4.8 (±1.2) 0.9774
CS0.5/PVA1B1 39.5 (±0.4) 71 (±4) 78 (±4) 83 (±3) - -
CS0.5/PVA1B2 45.9 (±1.4) 74 (±2) 75 (±4) 82 (±3) 2.9 (±0.4) 0.9292
CS1/PVA1E1 56 (±2) 74 (±2) 52 (±3) 48.1 (±1.1) 28.6 (±1.6) 0.9922
CS1/PVA1E2 62 (±2) 75 (±2) 44 (±2) 43 (±2) 31.7 (±1.1) 0.9934
CS1/PVA1B1 53.5 (±1.5) 63 (±2) 65 (±3) 61.7 (±1.2) 4.0 (±1.4) 0.9736
CS1/PVA1B2 60.4 (±1.1) 70 (±2) 61 (±3) 59.3 (±1.1) 7.2 (±0.9) 0.9821
CS1/PVA0.5E1 70 (±3) 77 (±3) 47 (±2) 42.5 (±1.4) 16.3 (±1.1) 0.9883
CS1/PVA0.5E2 71 (±3) 84 (±4) 44 (±2) 41 (±2) 16.6 (±1.4) 0.9856
CS1/PVA0.5B1 63 (±2) 76 (±4) 84 (±5) 69 (±3) - -
CS1/PVA0.5B2 69 (±3) 76 (±4) 63 (±4) 58 (±3) 6.7 (±1.6) 0.9904

*, **-SReq and Elastic modulus were determined for the hydrogels obtained after six freeze–thaw cycles.