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. 2021 Sep 20;22(18):10131. doi: 10.3390/ijms221810131

Table 1.

Evidence linking exosomes to tumor progression and therapeutic resistance.

Reference Cancer Type Exosomal Correlation
[47] Glioma Exosomes transport EGFRvIII to cells that did not previously have it
[48] Pancreatic Cancer cell exosomes are able to instigate malignant cell transformation
[49] Colon Exosomes can mediate transfer of mutant KRAS to wild-type colon cells
[50] Breast Exosomal ncRNA can confer drug resistance in breast cancer
[51] Prostate Exosomes confer docetaxel resistance from cell to cell
[52] Prostate Plasma-derived exosomes derived from patients with CRPC are significantly smaller than those from patients with localized disease
[14] Prostate Detection of AR-V7 in exosomal RNA can predict resistance to hormone therapy in metastatic disease
[53] Prostate Higher exosomal FABP5 content is correlated with higher Gleason score prostate cancer
[54] Prostate Increased exosomal survivin levels correspond to higher Gleason scores