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. 2021 Sep 20;22(18):10131. doi: 10.3390/ijms221810131

Table 2.

Summary of the biomarker value of exosomes in cancer.

References Biomarker Value of Exosomes in Cancer
[37] 44% of exosomal cargo transcripts are comprised of ncRNAs with potential biomarker utility
[37] Higher exosomal gene expression of immune pathway genes such as IRF6, IFNAR1, TNFRSF12, and STAT5
[37] Higher exosomal gene expression of apoptosis and DNA repair genes such as HSPB1 and SDC1
[37] Higher exosomal gene expression of androgen-regulated genes such as AR, KLK2, CDKN1A, KLK10, JUN, and B2M
[23] PCA3 and TMPRSS2:ERG mRNA can be isolated from urinary exosomes
[54] Prostate cancer patient plasma contains higher levels of survivin