Table 4.
Body weight gains and organ weights of C57Bl6 mice after 4 weeks of furan treatment.
| Furan (mg/kg bw) |
Survived Mice (No.) |
Final Body Weight (g) |
Liver | Spleen | ||
|---|---|---|---|---|---|---|
| Mean ± SE | Weight (g) Mean ± SE |
Hepatic a Index Mean ± SE |
Weight (mg) Mean ± SE |
Splenic a Index Mean ± SE |
||
| 0 | 5 | 23.3 ± 1.4 | 1.03 ± 0.1 | 4.40 ± 0.6 | 73.9 ± 11.5 | 0.32 ± 0.5 |
| 8 | 6 § | 24.1 ± 0.4 | 1.29 ± 0.1 | 5.37 ± 0.3 * | 84.2 ± 8.6 | 0.35 ± 0.02 |
| 15 | 5 | 22.6 ± 2.7 | 1.25 ± 1.2 | 5.50 ± 0.4 ** | 85.1 ± 24.4 | 0.39 ± 0.15 |
| 30 | 6 | 22.0 ± 0.9 | 1.18 ± 0.3 | 5.31 ± 1.3 | 75.7 ± 16.4 | 0.34 ± 0.08 |
* p < 0.05; ** p < 0.01 (Student t test); § One mouse from this group died during treatment; a The organ index formula is: organ weight (g)/body weight (g) × 100.