Table 3.

Correlation analysis of IC₅₀ of the KATP channel blockers to inhibit the currents of recombinant channels in cell lines vs. their Proportional Reporting Ratio (P.R.R.).

P.R.R. of KATP Channel Blockers	IC50 (M) of KATP Channel Blockers	Equations and Coefficient of Correlation
hypoglycaemia	KIR6.2-SUR1	y = aln(x) + b a = −0.708 b = −8.2542 R2 = 0.7849
muscular weakness rhabdomyolysis	KIR6.2-SUR2A	y = b0 + blnx1 + b2x2 b1 = −9.114 × 10−6 b2 = 3.505 × 10−5 b0 = −3.493 × 10−5 R2 = 0.83249
atrial fibrillation arrhythmias	KIR6.2-SUR2A KIR6.1-SUR2B	b1 = 4.0144 × 10−5 b2 = −2.708 × 10−5 b0 = 2.213 × 10−5 R2 = 0.602 b1 = −6.878 × 10−4 b2 = 4.342 × 10−4 b0 = 9.518 × 10−5 R2 = 0.699
atrial fibrillation hypertension	KIR6.1−SUR2B	b1 = 1.6465 × 10−3 b2 = −4.862 × 10−4 b0 = −3.851 × 10−4 R2 = 0.6177