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. 2021 Aug 29;11(9):860. doi: 10.3390/jpm11090860

Table 3.

Laboratory Tests for Diagnosis of Atopic Diseases.

Blood

• IgA, IgG1, IgG4, IgE

• Immune IgE (RAST for alpha-gal, casein, dust, dust mites, egg, fungi, grass, gluten, pollen)

• Anti-IgE receptor antibody (basophil activation or histamine release test)

• CCL2, CXCL8 (IL-8)

• Chromogranin A *

• Eosinophilic cationic protein (ECP)

• Food Intolerance Panel

• Heparin

• IL-4, IL-6, IL-31, IL-33

• Prostaglandin D2 (PGD2)

• Tryptase

Urine collected for 24 h or first morning void (must be kept and sent cold)

• N-methylhistamine (NMH) or methylimidazole acetic acid (MIA)

• PGD2

• 23BPG=2,3-Dinor-11β-PGF2α

* Should be measured after one week of NO antacids, otherwise there is a high chance of false positive results. Elevated chromogranin A is not indicative of atopy, but of a somewhat similar condition called carcinoid syndrome associated with activated enterochromaffin cells in the gut.