Table 4.

Different histamine-1 receptor antagonists.

Generic Drug	(Trade Name)
Bilastine *	Nonsedating, non-metabolized
Cetirizine	Nonsedating
Cyproheptadine	Antiserotonergic
Diphenhydramine	Sedating
Hydroxyzine	Anxiolytic
Ketotifen *	Anti-eosinophilic
Loratadine	Nonsedating
Rupatadine *	Anti-PAF (Platelet activating factor), mast cell inhibitor
Tricyclic Antidepressants
Amitriptyline	Weight gain
Doxepin	Also histamine-2 receptor antagonist
Phenothiazines
Promethazine	Antiemetic
Prochlorperazine	Antiemetic, mast cell inhibitor

* Available only via compounding in the United States.