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. 2021 Sep 14;10(9):2418. doi: 10.3390/cells10092418

Figure 1.

Figure 1

Historical Timelines of Endocrine FGFs. Historical perspective of notable events in the discovery and development of endocrine FGFs. (Panel-A): FGF19 timeline from discovery to the most recent clinical trial for FGF19-based biomedical application, aldafermin. (Panel-B): FGF21 timeline from discovery to the most recent findings pertaining to the structure of FGF21. (Panel-C): FGF23 timeline from discovery to the most recent findings regarding its therapeutic role in treating acute inflammation.