Table 5.
Enrichment analysis of the target genes of the altered microRNAs in inflammatory bowel disease-associated colorectal cancer
Pathway | P value | Adjusted P value |
VEGFA-VEGFR2 signaling pathway | 2.577e-31 | 1.203e-28 |
TGF-beta signaling pathway | 1.823e-23 | 4.257e-21 |
EGF/EGFR signaling pathway | 6.399e-20 | 9.961e-18 |
DNA damage response (only ATM dependent) | 8.953e-20 | 1.045e-17 |
Oncostatin M signaling pathway | 1.426e-18 | 1.322e-16 |
Integrated breast cancer pathway | 1.699e-18 | 1.322e-16 |
Insulin signaling | 4.429e-18 | 2.955e-16 |
Focal adhesion | 2.120e-17 | 1.238e-15 |
Signaling pathways in glioblastoma | 4.047e-17 | 2.100e-15 |
ErbB signaling pathway | 4.559e-16 | 2.129e-14 |