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. 2021 Sep 15;13(9):1043–1061. doi: 10.4251/wjgo.v13.i9.1043

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©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/

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Disappearing liver metastasis. A: A 36-year-old man presented with a solitary synchronous colorectal liver metastasis to segment 5, seen on staging positron emission tomography-computed tomography scan; B: After 6 cycles of CAPOX plus bevacizumab, followed by pelvic radiation (5040 cGy in 28 fractions), subsequent magnetic resonance imaging (shown) and intraoperative ultrasound were unable to localize the lesion; C: He was then lost to follow-up and returned 18 mo later with an intrahepatic recurrence, seen on surveillance computed tomography scan and confirmed with tissue biopsy.