3-OHM |
3-hydroxymelatonin |
Aβ |
β-amyloid peptide |
AD |
Alzheimer’s disease |
ADP |
adenosine diphosphate |
AICD |
amyloid precursor protein intracellular domain |
ALS |
amyotrophic lateral sclerosis |
ANT |
adenine nucleotide translocator |
APP |
amyloid precursor protein |
ASC |
apoptosis-associated speck-like protein containing a C-terminal caspase recruitment domain |
ATP |
adenosine triphosphate |
CL |
cardiolipin |
CYB5R3 |
NADH-cytochrome b5 reductase 3 |
Cyt |
c cytochrome c |
DDX3(X) |
DEAD-box RNA helicase |
DNA |
deoxyribonucleic acid |
eIF2a |
eukaryotic translation initiation factor 2 alpha |
ER |
endoplasmic reticulum |
FTO |
frontotemporal dementia |
FUS |
fused in sarcoma |
H+ |
proton |
H2O2
|
hydrogen peroxide |
IDP |
intrinsically disordered protein |
IDR |
intrinsically disordered region |
IMM |
inner mitochondrial membrane |
Lo
|
liquid-ordered |
Lc
|
circular liquid-condensed |
Ld
|
liquid-disordered |
LLPS |
liquid–liquid phase separation |
m6A |
N6-methyladenosine |
mM |
millimolar |
μM |
micromolar |
MDM2 |
mouse double minute 2 homolog |
MLO |
membraneless organelle |
MAM |
mitochondria-associated membrane |
MOM |
mitochondrial outer membrane |
mPTP |
mitochondrial permeability transition pore |
mRNA |
messenger RNA |
MT |
microtubule |
NE |
nuclear envelope |
NFT |
neurofibrillary tangles |
NLRP3 |
NLR pyrin domain containing 3 (inflammasome) |
nM |
nanomolar |
NPC |
nuclear pore complex |
O2•−
|
superoxide radical |
•OH |
hydroxyl radical |
•OOH |
hydroperoxyl radical |
OXPHOS |
oxidative phosphorylation |
PD |
Parkinson’s disorder |
PDC |
pyruvate dehydrogenase complex |
PDK |
pyruvate dehydrogenase kinase |
Pi |
inorganic phosphate |
PLD |
prion-like domain |
PML |
promyelocytic leukemia proteins |
PTM |
post-translational modification |
RNA |
ribonucleic acid |
RBP |
RNA-binding protein |
RNP |
ribonucleoprotein |
ROS |
reactive oxygen species |
RP |
ribosomal protein |
SG |
stress granule |
SUMO |
small ubiquitin-like modifier |
TCA |
tricarboxylic acid (cycle) |
TDP-43 |
TAR DNA-binding protein 43 |
Ub |
ubiquitin |
UCP1 |
uncoupling protein 1 |
UPS |
ubiquitin-protease system |
VDAC |
voltage-dependent anion channel |
ZFP217 |
zinc finger protein 217 |