Table 2.
Operating findings, postoperative complications, and pathology by surgical technique compared in the matched cohort.
| Matched Cohort | |||
|---|---|---|---|
| LG n = 624 |
OG n = 624 |
p-Value | |
| Total operative time (minutes) | <0.0001 # | ||
| Median (IQR) | 180 (150–210) | 240 (180–300) | |
| Mean (SD) | 192.7 (72.6) | 243.7 (86.5) | |
| Conversion to open surgery, n (%) | 12 (1.9) | N/A | N/A |
| N. harvested lymph nodes | <0.0001 # | ||
| Median (IQR) | 32 (24–40) | 28 (22–38) | |
| Mean (SD) | 33.2 (12.6) | 31.3 (14.1) | |
| N. metastatic lymph nodes | 0.400 # | ||
| Median (IQR) | 3 (0–11) | 3 (0–11) | |
| Mean (SD) | 7 (9.1) | 7.6 (10.8) | |
| R factors | 0.021 | ||
| R0 | 604 (96.8) | 587 (94.1) | |
| R + (R1 − R2) | 20 (3.2) | 37 (5.9) | |
| Neoadjuvant chemotherapy, n (%) | 0.493 | ||
| Yes | 20 (3.2) | 15 (2.4) | |
| No | 604 (96.8) | 609 (97.6) | |
| Neoadjuvant radiotherapy, n (%) | 1.000 | ||
| Yes | 1 (0.2) | 0 (0) | |
| No | 623 (99.8) | 624 (100) | |
| Histology types in detail, n (%) | 0.767 | ||
| Differentiated (total) | 405 (64.9) | 400 (64.1) | |
| Tubular well-differentiated | 358 (57.4) | 301 (48.2) | |
| Tubular moderately differentiated | 40 (6.4) | 91 (14.6) | |
| Papillary | 7 (1.1) | 8 (1.3) | |
| Poorly differentiated/Undifferentiated (total) | 219 (35.1) | 224 (35.9) | |
| Mucinous | 69 (11.1) | 50 (8) | |
| Signet ring cell | 97 (15.5) | 96 (15.4) | |
| Poorly differentiated solid/non-solid type * | 43 (6.9) | 76 (12.2) | |
| Undifferentiated | 10 (1.6) | 2 (0.3) | |
| Postoperative hospital stay (days) | <0.0001 # | ||
| Median (IQR) | 10 (9–13) | 14.8 (10–17) | |
| Mean (SD) | 12.2 (8.2) | 13 (7.6) | |
| Patients with complications, n (%) | 94 (15.1) | 133 (21.3) | 0.004 |
| Clavien-Dindo complications, n (%) | 0.433 | ||
| I | 9 (6.4) | 16 (9.3) | |
| II | 106 (74.6) | 121 (70) | |
| IIIa | 8 (5.6) | 7 (4) | |
| IIIb | 8 (5.6) | 17 (9.8) | |
| IVa | 8 (5.6) | 10 (5.8) | |
| IVb | 2 (1.4) | 0 (0) | |
| V | 1 (0.8) | 2 (1.1) | |
| Total | 142 (100) | 173 (100) | |
| Severe in-hospital complications, n (%) | 0.689 | ||
| Clavien-Dindo ≥ 3 | 27 (19) | 36 (20.8) | |
| Reoperation, n of patients (%) | 10 (1.6) | 17 (2.7) | 0.392 |
| In-hospital mortality, n (%) | 1 (0.2) | 2 (0.3) | 0.563 |
OG: open gastrectomy; LG: laparoscopic gastrectomy; n = number; # = Mann–Whitney U test; ml: milliliter; N/A: not applicable; IQR: interquartile range; SD: standard deviation; * only 2 patients with poorly differentiated: non-solid type (por2).