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. 2021 Sep 14;13(9):1470. doi: 10.3390/pharmaceutics13091470

Table 1.

Physicochemical characterization of the NPs.

Sample Diameter ζ Potential (mV) PDI Encapsulation Efficiency (% w/w)
NIR poly(I:C) R848 MIP3α
NP(NIR + pIC + R848 + MIP3α)-PEG 249.6 ± 85.4 −21.4 ± 4.75 0.178 ± 0.042 62.4 ± 6.9 43.6 ± 8.6 54.2 ± 8.9 59.3 ± 7.3

Physicochemical characterization of the PLGA-PEG NPs containing immunostimulatory agents. The PLGA NPs were characterized as reported previously [20], by dynamic light scattering and zeta potential measurements. The size and zeta potential data represent the mean value ± SD of 10 readings of one representative batch. The concentration of the NIR dye was measured by fluorescence. The concentration of poly(I:C), R848, and MIP3α was determined by RP-HPLC analysis.