Table 1.
Initial and Final Body Weights, Heart Weights, Glycemic Parameters and Plasma Renin Activity among the Four Groups of Rats.
| Dietary Regimen | n | Initial Weight (g) |
Final Weight (g) | Heart Weight (g/kg) | Fasting Glucose (mg/dL) |
Fasting Insulin (ng/mL) |
G:I Ratio (×106) | PRA (ngAngI/mL/hr) |
|---|---|---|---|---|---|---|---|---|
| GCS-GCS | 9 | 125 ± 4 | 381 ± 9 | 3.3 ± 0.1 | 128 ± 13 | 1.14 ± 0.23 | 64.7 ± 6.4 | 1.82 ± 0.20 |
| FCS-GHS | 9 | 132 ± 4 | 347 ± 10 | 3.4 ± 0.1 | 129 ± 24 | 0.74 ± 0.12 | 74.6 ± 12.6 | 0.66 ± 0.12 * |
| FHS-GHS | 8 | 128 ± 3 | 362 ± 12 | 3.2 ± 0.1 | 126 ± 14 | 1.33 ± 0.12 | 31.6 ± 1.9 *,† | 1.35 ± 0.28 |
| FHS-FHS | 9 | 127 ± 5 | 366 ± 12 | 3.4 ± 0.1 | 118 ± 11 | 1.03 ± 0.17 | 39.1 ± 7.1 † | 1.09 ± 0.29 |
GCS-GCS, 20% glucose + 0.4% NaCl in Phases I–III; FCS-GHS, 20% fructose + 0.4% NaCl in Phase 1 and 20% glucose +4% NaCl in Phase III; FHS-GHS, 20% fructose + 4% NaCl in Phase 1 and 20% glucose + 4% NaCl in Phase III; FHS-FHS, 20% fructose + 4% NaCl in Phases I–III. PRA, plasma renin activity; G:I Ratio, glucose:insulin ratio. All groups except FHS-FHS were on 20% glucose + 0.4% NaCl in Phase II. Due to lack of sufficient plasma for insulin, n values for insulin and G:I Ratio are as follows: 5, 6, 7 and 7. Values are the mean ± SE; n as indicated per group. * p < 0.05 vs. GCS-GCS. † p < 0.05 vs. FCS-GHS.