Table 3.
A list of the metabolites determined in the cerebrospinal fluid of patients and identified as significantly different between the analyzed groups based on either analysis of variance (ANOVA) or non-parametric Kruskal–Wallis ANOVA, depending on the normality of distribution and variance equality. All values are expressed in micromoles.
| CSF | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| No. | Metabolite | Control (n = 10) | PD (n = 11) | APDs (n = 8) | ||||||
| Mean | SD | Median | Mean | SD | Median | Mean | SD | Median | ||
| 1 | Tyrosine | 8.93 | 3.09 | 7.98 | 14.09 | 4.44 | 13.00 | 13.42 | 5.81 | 10.65 |
| 2 | Putrescine | 0.13 | 0.03 | 0.14 | 0.19 | 0.05 | 0.20 | 0.16 | 0.05 | 0.16 |
| 3 | t4-OH-Proline | 0.42 | 0.13 | 0.39 | 1.06 | 0.88 | 0.76 | 0.74 | 0.15 | 0.74 |
| 4 | total DMA | 0.15 | 0.07 | 0.13 | 0.18 | 0.06 | 0.19 | 0.25 | 0.05 | 0.24 |
PD—Parkinson’s disease; APDs—atypical parkinsonian disorders; t4-OH-Pro—trans-4-hydroxyproline; DMA—dimethylarginine.