Table 4.

Demographic and clinical data of study cohorts.

Characteristics	Data
Discovery sample 1
No. of healthy volunteers	10
Age (years) median, range	33 (28–38)
Sex male/female	10/0
Fasting before blood draw (12 h)	yes
Non-smokers	yes
Timepoints	TTC 0.5 and 2 h
Validation sample 1
No. of healthy volunteers	10
Age (years) median, range	29 (21–54)
Sex male/female	7/3
Fasting before blood draw (12 h)	yes
Non-smokers	yes
Timepoints	TTC 0 (only EDTA plasma), 0.5, 1, 2 and 4 h
Validation sample 2
No. of healthy volunteers	23
Age (years) median, range	43 (25–60)
Sex male/female	6/17
Fasting before blood draw (12 h)	no
Non-smokers	yes
Timepoints	TTC 0.5, 1, 2 and 4 h
Validation sample 3
No. of rheumatologic patients	20
Age (years) median, range	70.5 (21–82)
Sex male/female	14/6
Disease	rheumatic
Fasting before blood draw (12 h)	no
Validation sample 3
No. of cardilogic patients	20
Age (years) median, range	64.5 (32–82)
Sex male/female	10/10
Disease	cardiovascular
Fasting before blood draw (12 h)	no
Validation sample 4
No. of cardiologic patients	40
Age (years) median, range	73 (48–89)
Sex male/female	20/20
Disease	cardiovascular
Fasting before blood draw (12 h)	no
Validation sample 4	Serum	EDTA plasma
No. of rheumatologic patients	30	49
Age (years) median, range	63 (32–88)	65 (20–90)
Sex male/female	14/16	23/26
Disease	rheumatic	rheumatic
Fasting before blood draw (12 h)	no	no