Figure 2.

SARS-CoV-2 N-human protein–protein interaction network. An interaction network (Cytoscape) between host factors and N proteins was generated. Interactomes in two cell lines were integrated (yellow nodes = interactors in HEK293T cells, orange nodes = interactors in Calu-3 cells, pink nodes = common interactors in both cell types). Curated host–host protein interactions from the CORUM and STRING databases are displayed as coloured subnetworks. Select human protein–protein complexes that are represented by at least three nodes are labelled.