Table 4. Univariate Cox regression analysis for the GSE50081 cohort.

T stage, N stage , Stage and Risk group were significantly associated with OS.

Variables		Number (percent)	HR (95 CI)	P-Value
Age				0.413
	<70y	61 (48.0%)	reference
	≥70y	66 (52.0%)	1.26 (0.72–2.20)	0.415
Gender				0.226
	Female	62 (48.8%)	reference
	Male	65 (51.2%)	1.41 (0.81–2.46)	0.228
Tstage				<0.001
	T1	43 (33.9%)	reference
	T2	82 (64.6%)	2.44 (1.22–4.90)	0.010
	T3+4	2 (1.6%)	11.7 (2.50–55.0)	0.002
N stage				0.008
	N0	94(74.0%)	reference
	N1	33 (26.0%)	2.14 (1.20–3.83)	0.010
Stage				0.001
	I	92 (72.4%)	reference
	II	35 (27.6%)	2.44 (1.38–4.32)	0.002
Risk_group				<0.001
	Low-risk	64 (50.4%)	reference
	High-risk	63 (49.6%)	2.72 (1.52–4.86)	<0.001