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. 2021 Sep 12;22(18):9851. doi: 10.3390/ijms22189851

Table 1.

The half-life (t1/2) and the drug retention values determined by second-order kinetic models for different systems.

PBS (pH = 7.4, 0.15 M NaCl)
t1/2 (min) td (min) Drug retention
pure vitamin B1 1.96 2.62 0.00
manufactured B1 tablet 2.57 3.49 1.31
liposomal carrier 8.71 10.94 4.44
Artificial gastric juice (pH = 1.5, 0.2 M KCl)
pure vitamin B1 2.96 3.11 0.00
manufactured B1 tablet 3.93 4.55 1.33
liposomal carrier 4.56 5.91 1.54