Table 6.
Variable | Outcome | Female (n = 402) | Male (n = 120) | Total (n = 522) | Sig. |
---|---|---|---|---|---|
Oral Side Effect Prevalence | Ulcers | 8 (2%) | 2 (1.7%) | 10 (1.9%) | 1.000 |
Vesicles | 6 (1.5%) | 2 (1.7%) | 8 (1.5%) | 1.000 | |
Blisters | 8 (2%) | 3 (2.5%) | 11 (2.1%) | 1.000 | |
White/Red Plaque | 6 (1.5%) | 1 (0.8%) | 7 (1.3%) | 1.000 | |
Angular Cheilitis | 6 (1.5%) | 0 (0%) | 6 (1.1%) | 0.345 | |
Halitosis | 6 (1.5%) | 1 (0.8%) | 7 (1.3%) | 1.000 | |
Xerostomia | 2 (0.5%) | 0 (0%) | 2 (0.4%) | 1.000 | |
Burning/Bleeding Gingiva | 16 (4%) | 1 (0.8%) | 17 (3.3%) | 0.139 | |
Taste Disturbance | 1 (0.2%) | 0 (0%) | 1 (0.2%) | 1.000 | |
Oral Paraesthesia | 4 (1%) | 0 (0%) | 4 (0.8%) | 0.578 | |
Intensity (0–10) | 0.16 ± 0.54 | 0.08 ± 0.36 | 0.14 ± 0.51 | 0.118 | |
Total (n) | 43 (10.7%) | 7 (5.8%) | 50 (9.6%) | 0.112 | |
Oral Side Effect Onset | 1–3 days | 9 (21.4%) | 1 (14.3%) | 10 (20.4%) | 0.467 |
1st Week | 8 (19%) | 2 (28.6%) | 10 (20.4%) | 1.000 | |
2nd Week | 9 (21.4%) | 1 (14.3%) | 10 (20.4%) | 0.467 | |
3rd Week | 11 (26.2%) | 2 (28.6%) | 13 (26.5%) | 0.742 | |
4th Week | 5 (11.9%) | 1 (14.3%) | 6 (12.2%) | 1.000 | |
Ulcers, Vesicles, and Blisters Location (n = 15) |
Tongue | 4 (36.4%) | 0 (0%) | 4 (26.7%) | 0.516 |
Palate | 2 (18.1%) | 1 (25%) | 3 (20%) | 1.000 | |
Labial/Buccal Mucosa | 6 (54.5%) | 1 (25%) | 7 (46.7%) | 0.569 | |
Gingiva | 3 (27.3%) | 2 (50%) | 5 (33.3%) | 0.560 | |
Lips | 1 (9.1%) | 1 (25%) | 2 (13.3%) | 0.476 | |
White or Red Plaque Location (n = 7) |
Tongue | 4 (66.7%) | 0 (0%) | 4 (57.1%) | 0.429 |
Soft Palate | 1 (16.7%) | 1 (100%) | 2 (28.6%) | 0.286 | |
Labial/Buccal Mucosa | 2 (33.3%) | 0 (0%) | 2 (28.6%) | 1.000 |
Chi-squared test (χ2), Fisher’s exact test, and Mann–Whitney test (U) were used with a significance level (Sig.) of < 0.05.