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CUR internalization after 24 h incubation of free CUR and CUR nanovesicles on (a) A549 and (b) THP-1 cells. (1) CUR 20 µg/mL—total lipids 1.4 mg/mL, (2) CUR 10 µg/mL—total lipids 0.7 mg/mL, (3) CUR 5 µg/mL—total lipids 0.35 mg/mL. Values were analysed using a one-way ANOVA, * p < 0.05; *** p < 0.001, **** p < 0.0001). (c) representative images of fluorescence microscopy of intracellular CUR on A549 cells.
