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Interaction between autophagy and the IKK–NF-κB axis. Both IKK and NF-κB can enhance autophagy by inducing the expression of autophagy-related proteins. Increased autophagic flux can inhibit IKK signaling by degrading IKK components. NF-κB signaling can act negatively on the autophagic process through the increase in autophagy repressors or through the decrease in autophagy inducers. Refer to the main text for proteins in each category in detail.
