Table 3.
MiRNA expression results: Study II.
| miRNA | DLB vs. CTRLs | AD vs. CTRLs | DLB vs. AD |
|---|---|---|---|
| n | 22 vs. 16 | 15 vs. 16 | 22 vs. 15 |
| let-7d-5p | |||
| expr change 1 | 0.21 | 1.40 | 0.14 |
| dev range 2 | 0.024–1.73 | 1.12–1.75 | 0.02–0.98 |
| p-value 3 | 0.20 | 0.19 | 0.042 |
| miR-128-3p | |||
| expr change | 0.16 | 1.25 | 0.13 |
| dev range | 0.013–2.07 | 1.07–1.47 | 0.012–1.41 |
| p-value | 0.043 | 0.19 | 0.009 |
| miR-132-5p | |||
| expr change | 0.23 | 1.50 | 0.15 |
| dev range | 0.041–1.21 | 1.49–1.51 | 0.028–0.80 |
| p-value | 0.14 | 0.072 | 0.011 |
| miR-139-5p | |||
| expr change | 0.18 | 1.17 | 0.15 |
| dev range | 0.019–1.68 | 0.88–1.56 | 0.022–1.08 |
| p-value | 0.03 | 0.68 | 0.014 |
| miR-142-3p | |||
| expr change | 0.16 | 1.73 | 0.09 |
| dev range | 0.02–1.26 | 1.48–2.02 | 0.009–0.85 |
| p-value | 0.05 | 0.07 | 0.0026 |
| miR-146a-5p | |||
| expr change | 0.18 | 1.51 | 0.12 |
| dev range | 0.017–1.87 | 1.37–1.66 | 0.012–1.12 |
| p-value | 0.069 | 0.11 | 0.0089 |
| miR-150-5p | |||
| expr change | 0.011 | 0.34 | 0.031 |
| dev range | 0.003–0.034 | 0.29–0.40 | 0.008–0.118 |
| p-value | <0.0001 | 0.029 | <0.0001 |
| miR-25-3p | |||
| expr change | 0.20 | 1.15 | 0.17 |
| dev range | 0.026–1.52 | 0.94–1.41 | 0.02–1.08 |
| p-value | 0.03 | 0.85 | 0.025 |
| miR-26b-5p | |||
| expr change | 0.19 | 1.59 | 0.12 |
| dev range | 0.02–1.83 | 1.49–1.70 | 0.013–1.07 |
| p-value | 0.092 | 0.075 | 0.0071 |
| miR-6747-3p | |||
| expr change | 0.62 | 1.39 | 0.44 |
| dev range | 0.24–1.55 | 1.23–1.56 | 0.20–0.99 |
| p-value | 0.92 | 0.25 | 0.25 |
1 expr change, expression change obtained by the ΔΔCt method after comparing two groups; 2 dev range, deviation range of the expression change; 3 p-value obtained by the Wilcoxon–Mann–Whitney followed by Dunn’s test for multiple corrections. Significant results are highlighted in bold.