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. 2021 Sep 10;10(9):1095. doi: 10.3390/antibiotics10091095

Table 2.

Amino acid sequences, type of synthesis and target groups of the AMPs discussed in this paper. Data were retrieved from the database of antimicrobial activity and structure of peptides [102]. GP: Gram-positive bacteria; GN: Gram-negative bacteria.

AMP Amino Acid Sequence Synthesis Target Group
Cathelicidin-BF KFFRKLKKSVKKRAKEFFKKPRVIGVSIPF Ribosomal GP and GN
Defensin GFGCPLDQMQCHRHCQTITGRSGGYCSGPLKLTCTCYR Ribosomal GP and GN
Nisin-P VXxKXLXxPGXKxGILMXXAIKxAxXGXHFG Ribosomal GP and GN
Gramicidin S VXLfPVXLfP Nonribosomal GP, GN, parasites, fungus, cancer cells, and mammalian cells
Polymyxin Colistin XTXXXlLXXT Synthetic GN
Mellitin GIGAVLKWLPALIKRKRQQ Synthetic GP, GN, and mammalian cells
Sm-Piscidin KGARQAWKDYKYNRNMQKMNQGYGQQGG Ribosomal GP, GN, and fungus
Jellein-1 PFKISIHL Ribosomal GP, GN, and mammalian cells
Aurein-1.1 GLFDIIKKIAESI Ribosomal GP and GN
Citropin-1.1 GLFDVIKKVASVIGGL Ribosomal GP, GN, fungus, mammalian cells, and mollicute
Omiganan ILRWPWWPWRRK Synthetic GP, GN, fungus, and mammalian cells
ZY4 VCKRWKKWKRKWKKWCV Synthetic GP, GN, fungus, and mammalian cells
GL13K GKIIKLKASLKLL Synthetic GP, GN, insects, and mammalian cells
Chain201D KWIVWRWRFKR Synthetic GP, GN, and fungus
SAAP-148 LKRVWKRVFKLLKRYWRQLKKPVR Synthetic GP and GN
Lactococcin-G GTWDDIGQGIGRVAYWVGKAMGNMSDVNQASRINRKKKHKKWGWLAWVEPAGEFLKGFGKGAIKEGNKDKWKNI Ribosomal GP
Caerin-1.10 GLLSVLGSVAKHVLPHVVPVIAEKL Ribosomal GP, GN, viruses, and mammalian cells
Murepavadin LSYXXXXWXXASPP Synthetic GP, GN, cancer cells, and mammalian cells
Protonectin ILGTILPLLKGL Ribosomal GP, GN, cancer cells, fungus, and mammalian cells