Table 2.

The burden of comorbidities in the study group in the entire study group and depending on the recruitment mode (percentages).

Comorbidity	All Subjects n = 5479	Randomized n = 1164	Self-Selected n = 4315	p
Any comorbidities	14.0	18.0	12.9	<0.001
Coronary artery disease	0.6	1.1	0.4	0.01
Myocardial infarction	0.5	0.9	0.3	0.05
Heart failure	0.3	0.5	0.3	0.2
Valvular heart disease	0.4	0.8	0.3	0.07
Stroke	0.3	0.6	0.2	0.07
Chronic obstructive pulmonary disease	2.0	3.2	1.7	0.003
Asthma	6.7	7.1	6.6	0.6
Chronic Allergic Disease	11.5	9.9	11.9	0.06
Diabetes	6.5	9.7	5.6	<0.001
Cancer	4.2	6.4	3.6	<0.001
Chronic Rheumatological Disease	3.5	5.3	3.0	<0.001
Autoimmune disease	6.7	6.2	6.9	0.4

Legend: n—number of participants; p—p-value.