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. 2021 Sep 21;10(9):1136. doi: 10.3390/antibiotics10091136

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Effects of Tx I-b and carboplatin treatments (5 mg/kg) on 4T1 murine mammary carcinoma on the volume and weight of the tumor, and the body weight, n = 6. (A) LyeTx I-b decreased the tumor volume compared to the control group. (B) Representative images demonstrating a reduction in the size of tumor after treatment with LyeTx I-b. (C) LyeTx I-b reduced tumor weight. (D) No body weight differences over 25 days post-inoculation were observed on 4T1 murine mammary carcinoma model in the control, LyeTx I-b, and carboplatin groups. Data represent the mean ± SD, One-way ANOVA followed by Tukey’s multiple comparisons test, ** p < 0.01.