Figure 10.

Trends observed in published articles on the role of intracellular Ca²⁺ in cancer. (A) Schematic of finding articles published from 1990 to 2020 on intracellular Ca²⁺ in cancer. The number of articles published based on each advanced search filter combination is indicated in red. All the articles found with revised filter and subset-revised filter are further broken down into review articles, journal articles, and clinical studies. (B) Year-based distribution of the total number of published articles on intracellular Ca²⁺ in cancer differentiated per the search filters. The yearly distribution of the number of published articles identified using subset-revised filter is uniformly correlated with that of the revised filter; (C) Categorization of the number of published articles found using the revised filter per the main intracellular Ca²⁺ signaling molecule(s) in each study. (D) Categorization of the number of published articles found using the sub-set revised filter per the main intracellular Ca²⁺ signaling molecule(s) in each study. The articles were sorted by using the categories listed on the y-axis in panels (C,D) as keywords to be identified in the list of articles (title, abstract, and MeSH words) extracted with Revised Filter 1 by creating a dynamic search feature in Excel.