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. 2021 Aug 27;10(9):2218. doi: 10.3390/cells10092218

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Higher levels of PLEC mRNA expression are associated with poor ovarian cancer patient survival. (A,B) The KM plotter database was used to evaluate the prognostic value of PLEC mRNA expression in OC’s most common subtype, TP53 mutant serous carcinoma. High PLEC expression is a significant indicator of (A) overall survival and (B) post-progression survival in this subset of patients. (C) A differential expression analysis using Oncomine revealed PLEC to be significantly overexpressed in OC tissues.