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. 2021 Sep 25;19:97. doi: 10.1186/s12964-021-00743-w

Fig. 1.

Fig. 1

Ym155 regulates BMP signaling in lung cancer cells. A Immunoblot of tumors treated with JL5 for 4 days. B, C Western blot analysis of cells treated with Ym155 for 24 h. D, E Western blot analysis of BMP signaling following treatment with Ym155 for 24 h. F H1299 cells stably transfected with Id1-luciferase reporter were treated with Ym155 for 24 h and relative luminescence units (RVU) measured. Data shown is the mean of 2 independent experiments. G H1299 cells were transiently transfected with control vector or caBMPR1 then treated with Ym155. Western blot analysis of transfected cells treated with Ym155 for 24 h. H Data shows the mean of percent live cells of 3 independent experiments after being treated with Ym155 for 48 h. J Dose response curves of the number of live cells after being treated with Ym155 (I) or JL5 for 24 h