Table 2.
Presence of P. falciparum parasitaemia as assessed by nPCR, qPCR and PD-LAMP in community children with asymptomatic parasitaemia (CC), and positive control children with cerebral malaria (CM) or severe malarial anaemia (SMA)
| Study ID | Group | Parasite presence (nPCR) | Parasite density by qPCR (parasites/µL) | PD-LAMP |
|---|---|---|---|---|
| 7 | CCa | − | 0 | − |
| 8 | CC | − | 1 | + |
| 9 | CC | − | 0 | − |
| 10 | CC | + | 0 | − |
| 11 | CC | + | 0 | − |
| 12 | CC | + | 1 | − |
| 13 | CC | + | 56 | + |
| 14 | CC | + | 35 | + |
| 15 | CC | + | 12,749 | + |
| 16 | CC | + | 8.741 | + |
| 17 | CC | + | 100,669 | + |
| 18 | CMb | N.D.d | 377,406 | + |
| 19 | SMAc | N.D.d | 136,926 | + |
− = negative for P. falciparum DNA, + = positive for P. falciparum DNA
aCommunity controls
bCerebral malaria
cSevere malaria anaemia
dNot determined