Table 7.
Relationship between antidiabetic drugs and geriatric syndromes.
| Drugs Used for Diabetes | Metformin | Metformin and/or Other Oral Antidiabetics | Oral Antidiabetics+Insulin | Insulin | p-Value |
|---|---|---|---|---|---|
| ADL (mean ± SD) | 6.4 ± 1.9 | 6.1 ± 1.7 | 5.5 ± 1.7 | 5.7 ± 1.8 | <0.001 |
| handgrip strength (kg) (mean ± SD) |
25.1 ± 11.8 | 23.5 ± 9.5 | 18.1 ± 6.1 | 18.1 ± 8.7 | <0.001 |
| SMMI (kg/m2) (mean ± SD) |
12.1 ± 2.8 | 11.7 ± 3. 8 | 10.1 ± 3.5 | 10 ± 3.7 | <0.001 |
| gait speed (m/s) (mean ± SD) |
1.5 ± 1.1 | 1 ± 0.6 | 0.9 ± 0.6 | 0.9 ± 0.6 | <0.001 |
| calf circumfence (cm) (mean ± SD) |
43.9 ± 16 | 39.2 ± 9 | 42.7 ± 11.2 | 41.4 ± 8.8 | 0.01 |
cm: centimeter, kg: kilogram, kg/m2: kilogram per square meter, m/s: meter per second, ADL: activities of daily living, SMM: skeletal muscle mass, SMMI: skeletal muscle mass index.