Table 1.

Experimental design (n = 5) mice in each group.

S. Number	Groups	Experiment Conditions	Treatment	Duration
1	Light/Dark (LD) control	12 h:12 h light/dark [~150 lux]/[~0 lux]	1% CMC	3 weeks
2	Dim Light at Night (dLAN) control	12 h:12 h light/dim light [~150 lux]/[~5 lux]	1% CMC	3 weeks
3	Complete Darkness (DD) control	12 h:12 h dark/dark [~0 lux]/[~0 lux]	1% CMC	3 weeks
4	dLAN + Cur50	12 h:12 h light/dim light [~150 lux]/[~5 lux]	50 mg/kg curcumin	3 weeks
5	dLAN + Cur100	12 h:12 h light/dim light [~150 lux]/[~5 lux]	100 mg/kg curcumin	3 weeks
6	dLAN + Cur150	12 h:12 h light/dim light [~150 lux]/[~5 lux]	150 mg/kg curcumin	3 weeks
7	DD + Cur50	12 h:12 h dark/dark [~0 lux]/[~0 lux]	50 mg/kg curcumin	3 weeks
8	DD + Cur100	12 h:12 h dark/dark [~0 lux]/[~0 lux]	100 mg/kg curcumin	3 weeks
9	DD + Cur150	12 h:12 h dark/dark [~0 lux]/[~0 lux]	150 mg/kg curcumin	3 weeks