Table 1.
The clinical characteristics of the patients with CLL included in this study.
Patient No. | Gender | Age (Years) | Time from Diagnosis (Years) | Immunophenotype | Mutations | Treatment | ||||
---|---|---|---|---|---|---|---|---|---|---|
del(13q) | +12 | del(11q) | del(17p) | IGHV | ||||||
1 | M | 60 | 10 | CLL | Negative | Negative | Negative | Negative | ND | None |
2 | M | 68 | 1 | CLL | Negative | Negative | Negative | Negative | ND | None |
3 | F | 71 | 16 | CLL | ND | ND | ND | ND | ND | None |
4 | M | 65 | 11 | CLL | Negative | Positive | Negative | Negative | U | None |
5 | M | 58 | 10 | CLL | Positive | Negative | Positive | Negative | ND | Yes |
6 | M | 38 | 8 | CLL | Positive | Negative | Negative | Negative | U | Yes |
7 | M | 54 | 11 | CLL | Positive | Negative | Negative | Negative | U | Yes |
8 | M | 66 | 0 | CLL | Positive | Negative | Negative | Positive | U | Yes |
9 | M | 81 | 10 | CLL | Positive | Negative | Negative | Negative | ND | Yes |
10 | M | 87 | 1 | CLL | ND | ND | ND | ND | ND | None |
11 | F | 80 | 0 | CLL | Positive | Negative | Positive | Negative | U | Yes |
12 | F | 55 | 2 | CLL | Positive | Negative | Negative | Negative | Mut | None |
13 | M | 66 | 16 | CLL | Positive | Negative | Negative | Negative | ND | None |
14 | M | 66 | 10 | CLL | Positive | Positive | Negative | Negative | Mut | Yes |
15 | F | 63 | 11 | CLL | Positive | Negative | Negative | Negative | U | Yes |
16 | M | 79 | 7 | CLL | Positive | Negative | Negative | Negative | Mut | Yes |
17 | M | 73 | 0 | CLL | Negative | Negative | Negative | Positive | U | Yes |
18 | F | 64 | 5 | CLL | Positive | Negative | Negative | Positive | U | Yes |
19 | M | 44 | 4 | CLL | Positive | Negative | Negative | Negative | U | Yes |
20 | F | 72 | 6 | CLL | ND | ND | ND | ND | ND | None |
21 | M | 73 | 0 | CLL | Negative | Positive | Negative | Negative | U | Yes |
22 | M | 79 | 4 | CLL | Negative | Negative | Negative | Negative | ND | Yes |
23 | M | 52 | 8 | CLL | Positive | Negative | Negative | Negative | Mut | None |
24 | M | 63 | 1 | aCLL/MCL | Negative | Negative | Negative | Negative | ND | Yes |
25 | F | 64 | 4 | CLL | Positive | Negative | Positive | Negative | U | None |
26 | M | 75 | 10 | CLL | Positive | Negative | Negative | Negative | Mut | Yes |
27 | M | 71 | 1 | CLL | ND | ND | ND | ND | ND | None |
28 | F | 56 | 15 | CLL | Negative | Negative | Positive | Negative | U | Yes |
CLL, chronic lymphocytic leukemia; aCLL/MCL, atypical chronic lymphocytic leukemia/mantle cell lymphoma; IGHV, immunoglobulin heavy-chain variable region gene; M, male; F, female; ND, not determined; U, unmutated; Mut, mutated; del(13q), deletion of long arm of chromosome 13; +12, trisomy of chromosome 12; del(11q), deletion of long arm of chromosome 11; del(17p), deletion of short arm of chromosome 17.