Table 2.

The EC₅₀ values of autophagy inhibitors dorsomorphin, MRT68921, and chloroquine following 24-h and 48-h treatments of the primary CLL cells.

CLL Cells Patient No.	Dorsomorphin (µM)		MRT68921 (µM)		Chloroquine (µM)
	24 h	48 h	24 h	48 h	24 h	48 h
1	6.4	4.9	3.7	3.4	16.0	5.6
2	5.2	4.4	3.0	2.6	14.0	8.8
3	5.9	3.0	3.7	2.7	23.8	13.7
4	6.5	5.4	4.1	2.3	13.1	10.1
5	7.8	5.5	5.2	4.5	60.1	22.3
6	4.4	3.5	3.2	1.8	60.8	14.3
7	7.3	3.1	4.8	3.4	21.3	7.3
8	6.5	3.7	3.8	2.6	53.1	23.5
9	8.6	5.6	4.8	4.0	19.9	4.1
10	5.0	2.8	4.8	3.3	46.4	7.6
11	3.1	2.0	1.0	0.2	4.1	2.1
12	12.2	11.1	8.0	7.5	46.3	24.0
13	1.8	1.6	1.2	0.7	6.6	4.6
14	14.2	9.6	10.8	9.7	60.4	23.1
15	6.5	4.4	4.5	3.4	29.7	14.3
16	6.4	5.2	4.2	3.4	>100	45.2
17	2.6	2.9	1.6	1.3	28.4	19.4
18	8.5	7.5	5.7	5.2	37.0	24.9
19	12.4	7.6	8.9	6.8	92.7	29.3
20	3.6	3.0	3.6	3.5	21.1	13.4
21	9.0	4.5	5.6	2.5	54.9	16.7
22	2.9	2.0	1.3	1.3	22.4	8.5
23	7.0	5.3	3.7	3.2	32.8	19.1
24	9.9	9.2	6.5	5.0	>100	67.4
25	5.1	3.9	2.4	1.2	51.5	22.0
26	3.5	2.0	4.3	4.0	18.5	9.0
27	3.7	3.1	3.2	3.0	31.9	24.9
28	2.7	2.6	2.4	2.3	30.9	11.9
Mean ± SD	6.4 ± 3.1	4.6 ± 2.4	4.3 ± 2.3	3.4 ± 2.1	34.5 ± 20.8	17.8 ± 13.6