Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Regulation of luciferase activity via miRNA predicted binding sites. (A) Sequences of predicted miRNA binding sites: wild-type (wt) and mutated (mut). Predicted seed regions are framed. Mutations within binding sites of (B) miR-144, (C) miR-134, partially (D) miR-141, but not (E) miR-382, ablated ability of corresponding miRNAs to regulate luciferase signal. Each dot represents mean value from one plate with 4 wells per group. *—p-value < 0.05, **—p-value < 0.01, ***—p-value < 0.001.
