Figure 2.

Histological analysis of wound healing. Haematoxylin and Eosin staining of cross sections. Histology showed a clear wound edge (indicated by dotted line), separation of strata (^), swelling of cells (X) and pycnotic nuclei (*) 1 day after burning. On day 7 and day 14, wound closure could be observed. Images in the boxes show the same region of the model. The wound edge is progressing under the remaining dead tissue. During the healing process a new epidermis is formed, containing all layers. (Images from 1 out of 3 biological replicates in independent test runs with 1 technical replicate each).