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. 2021 Sep 14;13(18):4607. doi: 10.3390/cancers13184607

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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USP44 promoter methylation and its correlation to deletions in the genomic region between TMPRSS2 and ERG genes in prostate adenocarcinoma patients. (A) Genome view of the chromosomal region Chr 21 (q22.2-q22.3). (B) Copy number variation data for Chr 21 (q22.2-q22.3) for meth^High and meth^Low groups. CNV data were obtained by TCGA-PRAD (Firehose Legacy). p values underneath the gene names were calculated with Mann-Whitney test. (C) Oncoprints indicating patients with gene deletion events within the chromosomal region Chr 21 (q22.2-q22.3) in meth^High (left) and meth^Low (right) group. Gene deletion frequencies (%) within each group are indicated on the right side of the oncoprint. Oncoprints were generated through cbioportal using CNV data from TCGA-PRAD (Firehose Legacy).