Table 1.
Demographic, clinical characteristics and laboratory parameters of COVID-19 patients
| Patient did not need ICU follow up (N = 582) | Patient need ICU follow up (N = 104) | p | |
|---|---|---|---|
| Age. median (IQR), years | 42 (30–54) | 67 (54–76) | < 0.001 |
| Age, years | < 0.001 | ||
| ≥ 56.5 | 121 (20.8) | 76 (73.1) | |
| < 56.5 | 461 (79.2) | 28 (26.9) | |
| Gender, female sex | 277 (47.6) | 39 (37.5) | 0.057 |
| Hypertension | 106 (12.8) | 42 (40.4) | < 0.001 |
| Diabetes | 58 (10.1) | 31 (29.3) | < 0.001 |
| Chronic pulmonary disease | 37 (6.4) | 22 (21.2) | < 0.001 |
| Malignity | 11 (1.9) | 10 (9.6) | < 0.001 |
| Coronary arterial disease | 37 (6.4) | 21 (20.2) | < 0.001 |
| Fever on admission | 198 (34.0) | 50 (48.1) | 0.006 |
| Dyspnea on admission | 113 (19.4) | 62 (59.9) | |
| Oxygen saturation, % | < 0.001 | ||
| > 94.5 | 463 (79.5) | 22 (21.2) | |
| ≤ 94.5 | 119 (20.4) | 82 (78.8) | |
| qSOFA | < 0.001 | ||
| 0 | 553 (95.0) | 38 (36.5) | |
| ≥ 1 | 29 (5.0) | 66 (63.5) | |
| White blood cell, × 109/L | 0.019 | ||
| ≥ 7.4 | 85 (14.6) | 36 (34.6) | |
| < 7.4 | 497 (85.4) | 68 (65.5) | |
| Monocyte, × 109/L | 0.006 | ||
| > 0.23 | 506 (86.9) | 70 (67.5) | |
| ≤ 0.23 | 76 (13.1) | 34 (32.7) | |
| NLR | < 0.001 | ||
| ≥ 3.5 | 173 (29.7) | 77 (74.0) | |
| < 3.5 | 409 (70.3) | 27 (26.0) | |
| Hemoglobin, g/L | < 0.001 | ||
| > 12.5 | 458 (78.7) | 61 (58.7) | |
| ≤ 12.5 g/L | 124 (21.3) | 43 (41.3) | |
| Platelet count, × 109/L | 0.031 | ||
| > 155 | 492 (84.5) | 73 (70.2) | |
| ≤ 155 | 90 (15.5) | 31 (29.9) | |
| GFR, ml/min/1.73 m2 | < 0.001 | ||
| > 96.2 | 369 (63.4) | 24 (23.1) | |
| ≤ 96.2 | 213 (36.6) | 80 (76.9) | |
| Aspartate transaminase, U/L | < 0.001 | ||
| ≥ 28.5 | 166 (22.5) | 79 (76.0) | |
| < 28.5 | 416 (71.5) | 25 (24.0) | |
| Alanine transaminase, U/L | 0.164 | ||
| ≥ 40.5 | 128 (22.0) | 33 (317) | |
| < 40.5 | 454 (78.0) | 71 (68.3) | |
| Albumin, g/L | < 0.001 | ||
| > 42.5 | 417 (71.5) | 23 (22.1) | |
| ≤ 42.5 | 166 (28.5) | 81 (77.9) | |
| Creatine kinase, U/L | 0.002 | ||
| ≥ 141.5 | 136 (23.4) | 45 (43.3) | |
| < 141.5 | 446 (76.6) | 59 (56.7) | |
| Lactate dehydrogenase, U/L | < 0.001 | ||
| ≥ 286.5 | 94 (16.2) | 71 (68.3) | |
| < 286.5 | 488 (83.8) | 33 (31.7) | |
| C-reactive protein, g/L | < 0.001 | ||
| ≥ 0.0275 | 123 (21.1) | 81 (77.9) | |
| < 0.0275 | 459 (78.9) | 23 (22.1) | |
| Procalcitonin, pg/mL | < 0.001 | ||
| ≥ 0.085 | 71 (12.2) | 71 (68.7) | |
| < 0.085 | 511 (87.8) | 33 (31.7) | |
| Troponin, ng/L | < 0.001 | ||
| ≥ 5.9 | 113 (19.4) | 78 (75.0) | |
| < 5.9 | 469 (80.6) | 26 (25.0) | |
| Prothrombin time, sec | < 0.001 | ||
| ≥ 12.5 | 153 (26.3) | 63 (60.6) | |
| < 12.5 | 429 (73.7) | 41 (39.4) | |
| aPTT, sec | 0.499 | ||
| ≥ 26.2 | 162 (27.8) | 40 (38.5) | |
| < 26.2 | 72.8 (72.2) | 64 (61.5) | |
| INR | < 0.001 | ||
| ≥ 1.06 | 183 (31.4) | 68 (65.4) | |
| < 1.06 | 399 (68.6) | 36 (34.6) | |
| Ferritin, µg/L | < 0.001 | ||
| ≥ 227.5 | 155 (26.6) | 70 (673) | |
| < 227.5 | 427 (73.4) | 34 (32.7) | |
| D-dimer, mg/L | < 0.001 | ||
| ≥ 0.535 | 210 (36.1) | 88 (84.6) | |
| < 0.535 | 372 (63.9) | 16 (15.4) | |
| Fibrinogen, g/L | < 0.001 | ||
| ≥ 3.40 | 210 (36.1) | 76 (73.1) | |
| < 3.40 | 372 (63.9) | 28 (26.9) | |
| Urea, mg/dL | < 0.001 | ||
| ≥ 36.1 | 116 (19.9) | 56 (53.8) | |
| < 36.1 | 466 (80.1) | 48 (46.2) | |
| Creatinine, mg/dL | < 0.001 | ||
| ≥ 0.96 | 125 (21.5) | 41 (39.4) | |
| < 0.96 | 457 (78.5) | 63 (60.6) | |
| Bilateral infiltration on CT | 250 (43.0) | 79 (70.6) | < 0.001 |
IQR, Interquartile range; NLR, Neutrophil to lymphocyte ratio; aPTT, Activated partial thromboplastin time; INR, International normalized ratio; CT, Computed tomography; GFR, Glomerular filtration rate; qSOFA, quick sequential organ failure assessment