Table 2.
Univariate analysis of potential predictive parameters for ICU admission in hospitalized COVID-19 patients
| Beta | OR | 95% CI L | 95% CI U | p | |
|---|---|---|---|---|---|
| Age, 56.5 years and older | 2.34 | 10.34 | 6.42 | 17.78 | < 0.0001 |
| Gender. female sex | −0.42 | 0.66 | 0.43 | 1.03 | 0.0577 |
| Hypertension | 1.11 | 3.04 | 1.96 | 4.91 | < 0.0001 |
| Diabetes | 1.35 | 3.84 | 2.30 | 6.27 | < 0.0001 |
| Chronic pulmonary disease | 1.37 | 3.95 | 2.01 | 6.98 | < 0.0001 |
| Malignity | 1.71 | 5.52 | 2.04 | 13.65 | 0.0004 |
| Coronary arterial disease | 1.32 | 3.73 | 2.00 | 6.42 | < 0.0001 |
| Number of comorbidities | 0.81 | 2.24 | 1.63 | 3.05 | < 0.0001 |
| Fever on admission | 0.59 | 1.80 | 1.14 | 2.75 | 0.0098 |
| Dyspnea on admission | 1.81 | 6.13 | 3.87 | 9.65 | < 0.0001 |
| Oxygen saturation, 94.5% and below | 2.67 | 14.50 | 8.93 | 25.80 | < 0.0001 |
| White blood cell, 7.4 × 109/L and above | 1.13 | 3.10 | 1.83 | 5.00 | < 0.0001 |
| Monocyte, 0.23 × 109/L and below | 1.17 | 3.23 | 1.95 | 5.28 | < 0.0001 |
| NLR, 3.5 and above | 1.91 | 6.74 | 4.25 | 11.37 | < 0.0001 |
| Hemoglobin, 12.5 g/L and below | 0.96 | 2.60 | 1.69 | 4.02 | < 0.0001 |
| Platelet count, 155 × 109/L and below | 0.84 | 2.32 | 1.41 | 3.67 | 0.0006 |
| Urea, 36.1 mg/dL and above | 1.55 | 4.69 | 3.06 | 7.42 | < 0.0001 |
| Creatinine, 0.96 mg/dL and above | 0.87 | 2.38 | 1.54 | 3.69 | < 0.0001 |
| GFR, 96.2 ml/min/1.73 m2 and below | 1.75 | 5.78 | 3.47 | 9.68 | < 0.0001 |
| Aspartate transaminase, 28.5 U/L and above | 2.07 | 7.92 | 5.02 | 13.39 | < 0.0001 |
| Alanine transaminase, 40.5 U/L and above | 0.50 | 1.65 | 1.02 | 2.64 | 0.0369 |
| Albumin, 42.5 g/L and below | 2.18 | 8.83 | 5.66 | 15.52 | < 0.0001 |
| Creatine kinase, 141.5 U/L and above | 0.92 | 2.50 | 1.61 | 3.85 | < 0.0001 |
| Lactate dehydrogenase, 286.5 U/L and above | 2.41 | 11.17 | 6.94 | 18.72 | < 0.0001 |
| C-reactive protein, 0.0275 g/L and above | 2.58 | 13.14 | 8.42 | 22.96 | < 0.0001 |
| Procalcitonin, 0.085 pg/mL and above | 2.74 | 15.49 | 10.19 | 25.67 | < 0.0001 |
| Troponin, 5.9 ng/L and above | 2.52 | 12.45 | 7.90 | 22.09 | < 0.0001 |
| Prothrombin time, 12.5 s and above | 1.46 | 4.31 | 2.86 | 6.52 | < 0.0001 |
| aPTT, 26.2 s and above | 0.48 | 1.62 | 1.05 | 2.43 | 0.0230 |
| INR, 1.06 and above | 1.42 | 4.12 | 2.67 | 6.54 | < 0.0001 |
| Ferritin, 227.5 µg/L and above | 1.74 | 5.67 | 3.73 | 9.13 | < 0.0001 |
| D-dimer, 0.535 mg/L and above | 2.28 | 9.74 | 5.95 | 18.92 | < 0.0001 |
| Fibrinogen, 3.40 g/L and above | 1.57 | 4.81 | 3.10 | 7.94 | < 0.0001 |
| Bilateral infiltration on CT | 1.43 | 4.20 | 2.68 | 7.33 | < 0.0001 |
| qSOFA:1 | 2.67 | 14.49 | 9.38 | 22.95 | < 0.0001 |
| qSOFA:2 | 3.26 | 25.92 | 15.96 | 36.14 | < 0.0001 |
NLR, Neutrophil to lymphocyte ratio; aPTT, Activated partial thromboplastin time; INR, International normalized ratio; CT, Computed tomography; GFR, Glomerular filtration rate; qSOFA, quick sequential organ failure assessment