UPS	ubiquitin-proteasome system
ER	endoplasmic reticulum
ATG	Autophagy-related genes
FDA	Food and Drug Administration
IM	isolation membrane
ULK1	Unc-51-like autophagy activating kinase 1
PI3K	Phosphatidylinositide 3-kinase
mTORC1	mechanistic target of rapamycin complex 1
AMPK	AMP-activated protein kinase
MOM	Mitochondrial outer membrane
MOMP	MOM potential
ERES	ER exit sites
MAMs	mitochondria-associated ER membranes
PI3P	Phosphatidylinositol 3-phosphate
DFCP1	double FYVE domain–containing protein 1
Ubl	ubiquitin-like
LC3	MT-associated protein 1 light chain 3
LC3-PE	LC3-phosphatidylethanolamine
LIR	LC3 interacting regions
Ambra1	Activating Molecule In Beclin1-Regulated Autophagy Protein 1
p62/ SQSTM1	Sequestosome-1
MTs	Microtubules
ALR	autophagic lysosome regeneration
IP3R	inositol 1,4,5-trisphosphate (IP3) receptor
JNK	c-Jun N-terminal kinase
BH3	Bcl-2 homology (BH) domain 3
3-MA	3-methyladenine
MLCK	myosin light chain kinase
PLK1	Polo-like kinase 1
DNA-PK	DNA-dependent protein kinase
ATM	ataxia–telangiectasia mutated
NP	Nanoparticle
NCT	National Clinical Trial
PSM	Petrosaspongiolide M
EPI	Epirubicin
Bcl-2	B-cell lymphoma 2
TP	tea polyphenol
MTAs	MT-targeting agents
CA-4	Combretastatin A-4
CA-4P	CA-4 phosphate
NAC	N-acetyl cysteine
ROS	reactive oxygen species
rhArg	recombinant human arginase
5-FU	5-fluorouracil
VCP	Valosin Containing Protein or p97
XN	xanthohumol
Sal A	salvianolic acid A
Sal B	salvianolic acid B
SCC	squamous cell carcinoma
CCC	circulating cancer cells
PTEN	phosphatase and tensin homolog deleted on chromosome 10
EMT	epithelial-mesenchymal transition
AKT	protein kinase B (PKB)
HIF-1α	hypoxia-inducible factor 1α
VEGF	Vascular endothelial growth factor
HCC	hepatocellular carcinoma
CRC	colorectal cancer
Dox	Doxorubicin
Cdk4	cyclin-dependent kinase 4
Hsp-90	heat shock protein-90
PARP-1	poly (ADP-ribose) polymerase 1
ALL	acute lymphoblastic leukaemia
CQ	Chloroquine
Baf A1	Bafilomycin A1
OC	Oblongifolin C
GUTK	guttiferone K
v-ATPase	vacuolar-type ATPase
LMP	lysosomal membrane permeabilization
SAR	structure-activity relationship
CR	Caloric restriction
SIRT1	Sirtuin 1
BNIP3/BNIP3L	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3/ligand
STAT3	Signal transducer and activator of transcription 3
RAGE	receptor for advanced glycation end products
MDR1	multidrug resistance protein 1
P-gp	P-glycoprotein
NLRP3	NLR family pyrin domain containing 3
EGCG	(−)-epigallocatechin-3-gallate
CGA	chlorogenic acid
EGC	(−)-epigallocatechin
ECG	(−)-epicatechin-3-gallate
NSCLC	non-small cell lung cancer
MAPK	mitogen-activated protein kinase
N-CoR	nuclear receptor co-repressor
HSC70	Heat shock cognate 71 kDa protein
TFEB	transcription factor EB
NF-κB	nuclear factor kappa-light-chain-enhancer of activated B cells
MMP	mitochondrial membrane potential
Nrf2	Nuclear Factor, Erythroid 2 Like 2
ARDs	age-related diseases
CRM	caloric restriction mimetic
p70S6K	phosphorylation of p70 ribosomal protein S6 kinase
SOCE	store operated calcium entry
TMZ	Temozolomide
MGMT	O6-methylguanine-DNA methyltransferase
TSC2	Tuberous Sclerosis Complex 2
PKC-δ	protein kinase C δ
TG2	Transglutaminase
CSCs	cancer stem cells
6-CEPN	6-C-(E-phenylethenyl)naringenin
BUC	bladder urothelial carcinoma
PERK	phosphorylated extracellular signal-regulated kinase
eIF2α	Eukaryotic initiation factor 2α
CHOP	C/EBP homologous protein
CaMMK	Calmodulin- dependent kinase protein kinase
IRE1α	inositol-requiring enzyme 1α
TNBC	triple-negative breast cancer
MPT	mitochondrial permeability transition
SERCA	Sarcoplasmic-/ endoplasmic reticulum sarco/ER Ca2+ ATPase
TG	Thapsigargin
TBMS1	Tubeimoside-1
ERK1/2	Extracellular signal-regulated kinase 1/2
PTP1B	protein-tyrosine phosphatase 1B
DRP1	dynamin-related protein
EEPP	ethanolic extract from P. polyphylla
DPPE	Diosgenin enriched P. polyphylla rhizome extract
BA	Betulinic acid
GRP78	glucose-regulated protein 78
CPT	Camptothecin
AP-1	Activator protein 1
miR-15a	microRNA-15a
BBR	Berberine
PDT	photodynamic therapy
TET	Tetrandrine
APL	acute promyelocytic leukemia
PA	pituitary adenoma
TRAIL	Tumor necrosis factor (TNF)-related apoptosis-inducing ligand
TRAF2	TNF receptor-associated factor 2
FAK	focal adhesion kinase
S6K1	70-kDa ribosomal S6 kinase 1
TQ	Thymoquinone
GBM	glioblastoma multiforme
LXRα	liver-X receptors α
ABCA1	ATP-binding cassette transporter A1
ccRCC	clear cell renal cell carcinoma
AR	androgen receptor
ω3-PUFAs	omega-3 polyunsaturated fatty acids
EPA	eicosapentaenoic acid
EPADA	EPA-dopamine
DHA	docosahexaenoic acid
DHADA	DHA-dopamine
MM	multiple myeloma
PBMCs	peripheral blood mononuclear cells
DCs	dendritic cells
PPARγ	peroxisome proliferator-activated receptor γ
Delta-T3	vitamin E Delta-tocotrienol
HDACIs	histone deacetylase inhibitors
TSA	trichostatin A
SAHA	suberoylanilide hydroxamic acid
FOXO1	forkhead box protein1
PRMT5	protein arginine methyltransferase 5
TRPV6	transient receptor potential cation channel, subfamily V, member 6
STC1	stanniocalcin 1
IGFBP2	insulin-like growth factor (IGF) binding protein-2
VSOAC	volume-sensitive organic anion channel
TauT	taurine transporter
MTP	mitochondrial transmembrane potential
CLL	Chronic Lymphocytic Leukaemia
ANT	Active, not recruiting
T	terminated
C	Completed
S	Suspended
R	Recruitment
NR	Not yet recruiting
U	Unknown
ATRA	all-trans retinoic acid
CyP	Cyclophosphamide
Cape	Capecitabine
PCOS	Polycystic ovarian syndrome
FME	familial Mediterranean fever
HEKs	human epidermal keratinocytes
CSCC	cutaneous squamous cell carcinoma cell
NTM	nontuberculous mycobacteria
LYNUS	lysosomal nutrient sensing machinery