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. 2021 Sep 21;22(18):10173. doi: 10.3390/ijms221810173

Figure 2.

Figure 2

ATP mobilizes Ca2+ from intracellular stores. (a) Examples of traces of [Ca2+] recorded in 16HBE cells showing the effects of repetitive extracellular application of 10 μM ATP in the absence of extracellular Ca2+. (b) Amplitude of the responses to the 1st, 2nd and 3rd ATP applications in the presence and in the absence of extracellular Ca2+. The data are represented as mean ± s.e.m. (n = 207, 482, 97, 249, 97 and 247 for the columns from left to right). The asterisks (**) denote statistically significant difference of the data obtained in the Ca2+-free condition (−Ca2+) with respect to the corresponding control data (+Ca2+) (p < 0.01; Kolmogorov-Smirnov test).