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. 2021 Sep 9;10(18):4071. doi: 10.3390/jcm10184071

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Pathway enrichment of target mRNAs of MiR-379/656 in breast cancer. (A) Interaction network plot of MiR-379/656 and negatively correlated target mRNAs. The purple-circled node represents the miRNAs, and the blue-squared nodes represent the mRNAs connected via edges representing interactions. (B) The dot-plot showing the top 20 statistically significant REACTOME pathways enriched for anti-regulated target mRNAs. Each point represents a pathway, arranged according to the overlapping count of genes, and the color of the point indicates −log10 adjusted p-value.