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Result of MVA for dapagliflozin l-proline layer formulation development: (a) loading plot with PC1 and PC2; (b) Pearson correlation coefficient. The blue lines and yellow boxes indicate the variables having a high correlation with dissolution. IDR, intrinsic dissolution rate; AOR, angle of repose; Bulk, bulk density; G.S., granule strength; C.U., content uniformity; Diss., dissolution; Contact, contact angle; Ribbon, ribbon density; Tapped, tapped density.
