Table 1.

ROC monomers MM/PBSA-binding free energy (kcal/mol) *.

Systems	Representative	Binding Free Energy	Standard Deviations
ROCs-GDP	S3GDP	−296.39	19.71
ROCs-GTP	S2GTP	−285.09	23.52
ROCsR1441C-GDP	S5GDPR1441C	−276.31	18.02
ROCsR1441G-GDP	S5GDPR144G	−274.93	17.48
ROCsR1441H-GDP	S2GDPR144H	−274.98	17.64

* The MM/PBSA-binding free energies between ROC monomers serve as an indicator for ROC dimerization extent.