Table 3.
Diagnostic performance parameters of LoopampTM Malaria (Pan/Pf/Pv) Detection kit.
| Kit | Samples | Nested PCR Results | HUMAN LAMP Results | |||||
|---|---|---|---|---|---|---|---|---|
| Cases Tested (Total) | Cases Positive (Total) | Cases Tested (Total) | Cases Positive (Total) | Sensitivity/ Specificity (95% CI) |
Positive Predictive Value (95% CI) | Negative Predictive Value (95% CI) | ||
| Loopamp™ Malaria Pan Detection Kit | Pf/Pv/Mix | 15/15/8 (38) |
15/15/8 (38) |
15/15/8 (38) |
15/15/8 (38) |
100% (90.75–100%) |
100% | 100% |
| Other Disease | 6 (6) |
0 (0) |
6 (6) |
0 (0) |
100% (54.07–100%) |
|||
| Loopamp™ Malaria Pf Detection Kit | Pf/Mix | 15/8 (23) |
15/8 (23) |
15/8 (23) |
15/8 (23) |
100% (85.18–100%) |
100% | 100% |
| Pv/Other Disease | 15/6 (21) |
0/0 (0) |
15/6 (21) |
0/0 (0) |
100% (83.89–100%) |
|||
| Loopamp™ Malaria Pv Detection Kit | Pv/Mix | 53/8 (61) |
53/8 (61) |
53/8 (61) |
53/7 (60) |
98.39% (91.34–99.96%) |
100% | 96.43% (79.44–99.47%) |
| Pf/Other Disease/Healthy Control | 15/6/6 (27) | 0/0/0 (0) | 15/6/6 (27) | 0/0/0 (0) | 100% (87.23–100%) | |||
Pf—Plasmodium falciparum; Pv—Plasmodium vivax; CI—confidence interval.