Figure 1.

Representative pictures of liver hematoxylin-eosin staining in the three groups. Normal liver histology in mice fed standard diet (Panel (A), original magnification 10×). Mice on HFD for 12 weeks showed severe mixed, micro- and macrovesicular steatosis (Panel (B), original magnification 10×). Two necro-inflammatory foci are visible in this field (Original magnification in the inserts 40×). Amelioration of liver histology in mice fed high fat diet + decaffeinated coffee for 12 weeks: absence of macrovesicular steatosis and inflammatory foci, reduction of microvescicular steatosis (Panel (C), original magnification 10×).